Skin Model Melanoma

Description

A 3D cross-section model of melanoma showing the atypical melanocytes extending from the epidermis into the dermis. The Breslow thickness, measured from the granular layer to the deepest point of invasion, is the single most important prognostic factor. Melanoma arises from malignant transformation of melanocytes, driven by UV-induced mutations commonly in the BRAF gene. The radial growth phase involves horizontal spread within the epidermis, while the vertical growth phase marks invasion into the dermis with metastatic potential. Clark levels describe anatomic depth of invasion through the dermal layers. Ulceration, mitotic rate, and lymphovascular invasion further refine staging. Melanoma skin section anatomy is essential teaching material in dermatology, oncology, and pathology. Medical advisory board reviewed. Clean geometry for rendering, real-time engines, and 3D printing.